AI 资讯

Hello everyone! I'm posting our research work as you might be interested in how we used ML to map part of the brain cells of the human hippocampus :) We used various human brain slices at high resolution (1 micrometer per pixel) and developed a custom segmentation pipeline that uses SoTA whole slice cell segmentation networks, like CellPoseSAM with good zero shot performances. We then refined semi-automatically those annotations and ensembled more finetuned models within the pipeline, adding a merging algorithm and a cell classification for 3 classes (excitatory and inhibitory neurons, and glial cells). But the high-res slices covered only a few parts of the hippocampus with respect to other slices scanned at 20x less the resolution where the cell nuclei are only 1 pixel wide. So we tried to map the high-res annotations we obtained to the low-res corresponding slices, and used a small UNet to supervise a density estimation task for 3 classes. We obtained a network that outputs a density map that can be sampled to obtain a probabilistic map of the cellular positions. Finally, to reconstruct the volume, we stacked together all the low-resolution density maps from all the slices that covered the hippocampus and obtained a point cloud, which you can see in the GIF along the corresponding anatomical CA (Cornus Ammonis) areas. The performances are still limited by the quantity of data and low-resolution slices, but we showed that the results were biologically plausible given previous estimates by other researchers. The paper was accepted at MICCAI 2026 a few weeks ago! Feedback is very welcome, especially on the density-estimation formulation and possible uses of the generated point cloud. submitted by /u/V_ector [link] [留言]

Splitting a PDF is one of those features that sounds trivial until you try to build it. Users expect range input ( 1-3, 5, 7-9 ), a per-page option, multiple file downloads, and zero server involvement. I built en.sotool.top/split/ to do exactly that. Here's how it works with Vue 3 and pdf-lib . Why Client-Side? PDFs often contain sensitive information. Contracts, medical records, financial statements. Even a "simple" splitting tool should not force users to upload files to a server. Client-side benefits: No upload bandwidth or size limits No server storage or cleanup Instant processing for normal files Works offline after the page loads The tradeoff is that everything has to run in the browser, which limits the libraries you can use. The Stack Vue 3 — UI and state pdf-lib — Load, manipulate, and save PDFs File API — Read the uploaded file lucide-vue-next — Icons npm install pdf-lib Loading the PDF and Counting Pages First, read the file into an ArrayBuffer and load it with pdf-lib . import { PDFDocument } from ' pdf-lib ' const pdfFile = ref < File | null > ( null ) const totalPages = ref ( 0 ) async function handleFile ( files : File []) { if ( files . length === 0 ) return pdfFile . value = files [ 0 ] const bytes = await files [ 0 ]. arrayBuffer () const pdf = await PDFDocument . load ( bytes ) totalPages . value = pdf . getPageCount () } Now we know how many pages exist and can show the split UI. Two Split Modes I offer two ways to split: by range and per page. Mode 1: Page Range Input Users type something like 1-3, 5, 7-9 . I parse it into groups of page indices. function parseRanges ( input : string , max : number ): number [][] { const groups : number [][] = [] const parts = input . split ( ' , ' ). map ( s => s . trim ()) for ( const part of parts ) { if ( part . includes ( ' - ' )) { const [ start , end ] = part . split ( ' - ' ). map ( Number ) const pages = [] for ( let i = start ; i <= end && i <= max ; i ++ ) { pages . push ( i - 1 ) } if ( pages . len

AI harnesses are the new vendor lock-in. To swap across harnesses easily without rewriting your app, LiteLLM launched the Lite-Harness SDK . Run your prompt across different harnesses: from lite_harness import query , AgentOptions prompt = " Fix the failing test " # Claude Code harness async for message in query ( prompt = prompt , options = AgentOptions ( harness = " claude-code " , model = " claude-opus-4-8 " ), ): print ( message ) # Codex harness async for message in query ( prompt = prompt , options = AgentOptions ( harness = " codex " , model = " gpt-5.5 " ), ): print ( message ) To enable cost controls, fallbacks, and logging, point it to your LiteLLM AI Gateway: export LITELLM_API_BASE = https://litellm.your-company.com/v1 export LITELLM_API_KEY = sk-litellm-... Engineer's Takeaway: This SDK unifies how you invoke the agents, not how they run internally. Each harness keeps its native loop and tool-calling semantics. It is perfect for A/B testing agent performance and centralizing costs, but remember it is in public beta, so custom tool injection might require extra work! The Problem I Had My team was building an internal bot to fix failing CI/CD tests. We had three engineers advocating for three different harnesses: one wanted Claude Code, another Codex, and another Pi AI. Without an abstraction layer, we would have had to maintain three forks of the same bot , with three different SDKs, three logging systems, and three ways to track costs. It would have been an impossible maintenance burden. How Lite-Harness Helped The SDK solved that exact pain point in three concrete dimensions : 1. Unified Invocation (Time Savings) Instead of maintaining three separate implementations, I had a single query() that routed to whichever harness I wanted. Switching from Claude Code to Codex was literally just changing a string in the options. This allowed us to do real A/B testing in production for two weeks without rewriting any core logic. 2. Cost Observability (The Killer

This is a tool to manage encrypted local backups of secrets. The core idea is that it aims to be usable without depending on it, meaning that even if the software disappeared from the face of Earth tomorrow, your data would still be recoverable. It also integrates nicely with NixOS (which is what I use, though it does not require NixOS to be used). I have summed up a bit of explanation and some answers to reasonable questions in a blog post: https://baldino.dev/blog/secs-man/

Prologue A while ago, I decided to develop a fully accessible main navigation component in React and write a series of articles documenting the steps it took to create a non-trivial accessible component. In my last development article , I finally completed the requirements for delivering an uncontrolled navigation component with a horizontal layout; with full keyboard functionality, along with adding the niceties of closing sublists when lists are closed and making sure any open sublist on the top row closes when focus shifts away from it. Rather than write an entirely new component for a mobile version, I'm going to modify the existing code. This first article outlines the steps necessary to set up and work with a controlled component. -— Note : This article is one of a series demonstrating building a React navigational component from scratch while considering accessibility through the process. The articles are accompanied by a GitHub repository with releases tied to one or more articles; each builds on the previous one until a fully implemented navigation component is complete. Each release and its associated tag contain fully runnable code for the article. The code discussed in this article is available in the release. and may be downloaded at release 1.0.0 . Links in the article will take you to the proper file in the tagged GitHub Repository. Because the code for this release is scattered across components, line numbers are added to make it easier to locate in the linked GitHub file. Line numbers are also provided for those who would like to follow along with a downloaded copy. While code examples are written in JavaScript for brevity, all actual code is written in Typescript and targets React 19.x, all while using vanilla CSS. Examples use Next.js v16.x, which is not required to run the navigation component. You can view the requirements for the Controlled Components Release along with previous requirements. Content Links Introduction Acceptance Criteria Contr

Here's a thing that surprises people the first time: an email sent through the API does not carry the signature the user set up in Gmail or Outlook. Provider signatures live in the provider's compose UI, and a programmatic send bypasses that entirely, so a message your app sends goes out with no signature at all unless you add one. The Nylas Signatures API is how you add it: store an HTML signature once, then attach it to a send by ID, and the signature gets appended to the message for you. This post covers signatures from two angles: the HTTP API your backend calls, and the nylas CLI for creating and testing one from the terminal. I work on the CLI, so the terminal commands below are the ones I reach for when I'm setting a signature up. Nylas signatures are separate from provider signatures The first thing to get straight is that these are not the user's existing signature. Nylas doesn't sync the signature configured in Gmail, Outlook, or any other provider, and that provider signature is never applied to mail sent through the API. If a message your app sends needs a sign-off, you create that signature with this API and attach it explicitly; there's no inheriting it from the connected account. That separation is deliberate, because a programmatic send is a different context from a person typing in their webmail. It does mean the responsibility is yours: a user who connects their mailbox expecting their familiar signature to appear on app-sent mail won't get it automatically. Stored signatures are grant-scoped, living at /v3/grants/{grant_id}/signatures , so each connected account has its own set, and they're HTML, so a branded sign-off with a logo and links works the same as a plain one. Create a signature Creating a signature is a POST /v3/grants/{grant_id}/signatures with a name and an HTML body . The name is for you, a label to find it by later; the body is the markup that gets appended to outbound mail. The response returns the signature with its ID, which is w

Software teams often face a false choice: move fast and accumulate technical debt, or build the perfect system and miss the deadline. But there may be a third path, the Best Simple System for Now (BSSN). This session introduces a pragmatic yet principled approach to software design: systems that are as simple as possible but no simpler. You’ll learn how to design code that is robust, change-friendly, and fit for purpose, while avoiding both gold-plating and corner-cutting. Through practical examples, we explore how to manage complexity, embrace uncertainty, and make sound decisions using concepts like Cost of Delay and RAROC. submitted by /u/goto-con [link] [留言]

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Europe’s extreme heat is shutting down power plants Europe is in the middle of a record-breaking heat wave, and the grid is being pushed to its limits as people turn to…

Link:- https://easy-assign.vercel.app Specially need some suggestions for ui Want some suggestions what to do next It is a freelance platform for students and freshers so they can easily get some gigs or post task for help they need In last 3 days I got around 500 users and some paid tasks What could be improved here ? The ui ,the way we make them apply ,profiles streaks or what? I want to scale it more and bring bigger projects here so what to do to make it more trustworthy ( I know first suggestion will be payment integration that will be done after 2000 users) submitted by /u/detective8421 [link] [留言]

Amazon’s latest India investment comes as global tech companies race to expand AI infrastructure in the country.

To celebrate its new status as No. 1 in JD Power's initial quality ranking among mainstream automakers, Ford is opening up about the challenges it has faced in recent years, especially around its reliance on automated systems in production and design. It turns out that those automated systems were not as robust as previously assumed, […]

Why organisational latency is becoming the biggest barrier to fully realising AI’s benefits

Introduction I'm Ahmer. I'm 19, I'm doing a 4-year Software Engineering degree at a fairly...

Here is a tool I built initially for myself to help with my German and Greek language studies. It started as a hack for creating Anki cards from native language audio. It extracts the words, finds their base forms (lemmas) and groups the examples by the lemma. At some point I realised that I have a transcription with word level timestamps that opens a lot of other opportunities. So I added a mode to click the first and last word in the transcript and it starts looping with the right gap and repe

From AirPods to on-ears, we’ve tested hundreds of pairs of headphones. Here are the best deals from Amazon’s biggest sale event.

This is a fascinating explotation of how LLMs fall for prompt injection attacks. It turns out that they learn to recognize the style of text in different role/instruction blocks, and not just the tags. Their conclusion: Role tags were a formatting trick that became the security architecture and the cognitive scaffolding of modern LLMs. We’ve shown that this architecture doesn’t survive into the model’s actual representations, and that such role confusion is linked to prompt injection. Unless LLMs achieve genuine role perception, we think injection defense will remain a perpetual whack-a-mole game. And the continuous nature of role boundaries opens the threat of injections designed to subtly shift LLM states through seemingly innocuous text, legally and at scale...

This year, FIFA is providing an AI agent that any team can use. Is it enough to level the playing field or will future winners be determined by which team can afford the best tools?

YouTube TV and DirecTV Stream customers may be eligible for a cash payout, after Disney agreed to pay $50 million to settle claims that it forced the services to increase their subscription prices. Anyone who was subscribed to YouTube TV or DirecTV Stream between April 1st, 2019, and March 31st, 2026 is eligible to claim […]

It’s day three of Prime Day, folks. We’re nearly 75 percent of the way through Amazon’s four-day sales event, and unsurprisingly, many deals are still sticking around. There have been all kinds of discounts on things like TVs, smart home gadgets, chargers, headphones, and more. Prime Day typically isn’t as big of a deal as […]

I like the idea of a solar-powered electric bike, but I don't think anyone should buy the new Phosgo Go5 - not yet, anyway. This "world's first AI solar e-bike" promises to "eliminate range anxiety," and is sold by a new brand out of China hoping to make a big splash by selling direct-to-consumer through […]