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Job titles of the future: Nature’s drug designer

In 2018, after nearly two decades working in Big Pharma, chemist Tim Cernak was ready to put his skills to a new use. For Merck, he’d developed precision therapies for cancer, HIV, and diabetes that could target disease while minimizing harm to healthy cells. But as a lifelong nature lover, he was increasingly concerned about…

2026-06-11 原文 →
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Inside soccer’s data renaissance

Imagine tuning in to the opening kickoff of a World Cup match and seeing a player intentionally send the ball all the way down the pitch and right out of bounds on the opponent’s end. Casual fans might scratch their heads. Where’s the logic in surrendering possession seconds into a game? If you were Jesse…

2026-06-11 原文 →
开发者

Why China is betting on big nuclear reactors

It’s a tale of two nuclear industries. In China, large reactors are coming together at a stunning pace. The country has nearly doubled its nuclear fleet since 2016, reaching nearly 60 gigawatts of total power capacity. The new facilities are nearly all gigawatt-scale pressurized-water reactors. Meanwhile, the US has built just two reactors in that…

2026-06-11 原文 →
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How We Built a Zero-Upload PDF Editor in WebAssembly to Beat the $108/yr Paywalls

For years, whenever I needed to merge two PDFs or compress a file to upload to a government portal, I would Google "compress PDF", click the first result, and inevitably hit a paywall. "You have reached your 2 free files per day limit." Worse, I was uploading sensitive documents—tax returns, medical records, and NDAs—to random servers in God-knows-where just to strip out some heavy images. I decided to build an alternative. I wanted it to be 100% free, have absolutely no daily limits, and most importantly: zero server uploads . Here is how we built PDF Pro using Next.js and WebAssembly to process PDFs entirely natively inside the user's browser. The Architecture: Why WebAssembly? Traditional PDF tools (like Smallpdf or iLovePDF) use a monolithic server architecture. You upload your file to their AWS bucket, their backend runs a Python or C++ script (usually using Ghostscript or a proprietary library) to manipulate the PDF, and then you download the processed file. This architecture is expensive (high bandwidth and compute costs) and creates a massive privacy liability. By compiling a C++ PDF manipulation library down to WebAssembly (WASM) , we inverted the architecture. 1. The Build Process We took pdf-lib and custom C++ compression algorithms and compiled them to a lightweight .wasm binary. When a user visits PDF Pro Compress , their browser downloads the ~2MB WASM file once and caches it. 2. Client-Side Processing When you drag and drop a 50MB PDF into the UI, it never hits our server. Instead, the browser's JavaScript engine passes a Pointer to the file data directly into the WebAssembly memory buffer. The WASM module executes native C++ speeds directly on your local CPU to compress or merge the document. Performance Benchmarks Because there is zero upload and zero download time, the performance metrics are staggering: 10MB PDF Compression (Cloud): ~15 seconds (Upload) + 4 seconds (Process) + 5 seconds (Download) = 24 seconds . 10MB PDF Compression (PDF Pro WASM)

2026-06-11 原文 →