AI 资讯
The quest to keep organs alive outside the body
This week, I covered a fascinating effort to preserve organs outside the body. There’s a huge shortage of donor organs, and one of the main reasons is time—they survive only a matter of hours outside the body, even when they’re kept on ice. Doctors dream of organ banks—stores of human organs that can be preserved…
AI 资讯
Supercooled kidneys have been transplanted into pigs in a “landmark achievement”
When it comes to organ donation, time is everything. As soon as an organ has been carefully removed from a donor’s body, it starts to deteriorate. Surgeons have a matter of hours to get it into a recipient. Leave it too long and the organ will become unusable. In most cases, organs will be kept…
AI 资讯
Science Corporation’s vision-restoring chip wins EU approval
"The thing that the space needs is a company making $100 million a year of revenue," Science Corp. CEO Max Hodak said.
开发者
Dimension Capital’s $800M third fund shows the intersection of science and compute is booming
The four-year-old firm's latest fund is 60% larger than its second vehicle announced 18 months ago.
科技前沿
On the run for 20 years, most-wanted fugitive caught hiding as a biotech exec
Ronald Fischer, aka Richard Graydon, was arrested in New York last week.
AI 资讯
Colossal Biosciences reportedly in talks to raise new capital at $20B–$30B valuation
The de-extinction startup is looking to double or triple its previous valuation, according to the report.
AI 资讯
The Off Switch: Mammals May Have Been Hiding the Power to Regrow Themselves All Along
A salamander can lose a leg and grow a new one. Cut a zebrafish's fin and it simply builds another. Mammals, us included, got the consolation prize: a scar. For a century, biologists assumed that somewhere on the evolutionary road to becoming warm-blooded, fast-moving animals, we traded regeneration away for good. Two research teams working on opposite sides of the planet have just made that assumption look wrong. The headline is almost hard to believe: the ability to regrow lost body parts may not have been deleted from our biology at all. It may simply have been switched off, and switches can be flipped back on. The genetic "remote control" that stopped working The first clue comes from a team at the National Institute of Biological Sciences in Beijing, working with genomics powerhouse BGI-Research. Publishing in Science , they zeroed in on a gene called ALDH1A2 , the instruction sheet for an enzyme that turns vitamin A into retinoic acid, a molecule that acts like a foreman on a construction site, telling cells where to go and what to build during tissue repair. Animals that regenerate freely crank this gene up at the wound site. Mice, it turns out, still carry the same gene. They've just lost the genetic "remote controls," the regulatory DNA that tells the gene to fire after an injury. The hardware is intact; the software command was disconnected somewhere in evolution. So the researchers reconnected it. By reactivating that dormant switch and restoring the flow of retinoic acid, they got mice to regenerate damaged outer-ear tissue, something a normal mouse simply cannot do. In their own words, they had found "a genetic switch involved in the evolution of regeneration." Meanwhile, in Texas, they regrew a limb joint The second piece of evidence lands the point with force. At Texas A&M, a group led by Dr. Ken Muneoka took a different route to the same destination. Instead of editing a genetic switch, they used a precisely timed sequence of two signaling proteins.
开发者
There’s a lot of hype around perimenopause. Don’t buy it.
Perimenopause has entered the chat. Perimenopause—and its better-known relative, menopause—used to be considered taboo. Not anymore, thanks at least in part to TV doctors and social media influencers. Perhaps it’s my age, but these days, both my algorithm and my conversations with friends increasingly swing toward perimenopause. Menopause is defined as the life stage that…
AI 资讯
Daniel Ek’s body-scanning startup Neko Health raises another $700M
Neko Health has developed proprietary body-scanning technology, which it couples with bloodwork, to assess a person's health.
AI 资讯
An Inventor of Apple's FaceID Wants to Analyze Your Brain's Health With AI
Gidi Littwin's new AI startup, Hemispheric, makes diagnostic brain scans for conditions like depression, PTSD, and Parkinson’s. He wants the technology to be as cheap and easy as a blood test.
AI 资讯
OpenAI researcher Miles Wang in talks to launch AI drug discovery startup valued at $2B
The funding discussions point to investor interest in applying AI to make breakthroughs in life sciences.
AI 资讯
Scientists’ Side Hustle? Using AI and Quantum Computing to Generate New Peptides
Researchers cobbled together funding and time to show how quantum computing could aid in the development of drugs to help underserved populations and combat rare diseases.
AI 资讯
Reed Jobs would rather talk about curing cancer than his last name
When we last sat down with Jobs at TechCrunch Disrupt nearly three years ago, his firm Yosemite was brand new and biotech was still reeling from its post-pandemic crash. Now, the venture outfit has a team of 17; a cluster of blockbuster drugs are all losing patent protection in roughly the same window, creating all kinds of new opportunities; and AI has gone from a curiosity to, in Jobs's words, a huge part of what Yosemite does. "I didn't expect Yosemite to be moving this fast," he said.
AI 资讯
Sperm donors need limits, says a European fertility group
Ties van der Meer doesn’t know how many siblings he has. The 47-year-old was conceived at a private fertility clinic in the Netherlands using sperm provided by an anonymous donor. After the Netherlands banned anonymous donation in 2004, the doctor who ran the clinic destroyed records that might have identified those donors, he says. He…
AI 资讯
A device that revives eyeballs from dead donors could make eye transplants possible
It’s not easy to transplant a whole human eye. The surgery is difficult. And the eyes themselves start to degenerate as soon as they’ve left the body. When surgeons attempted it a few years ago, the newly-transplanted eye wasn’t able to see. But researchers believe they might have a solution: a device that maintains and…
AI 资讯
The UK’s generational tobacco ban might not work. I’m supporting it anyway.
As the parent of two little girls, I often think about how their childhood is different from mine. The seven-year-old is learning about AI at school. The five-year-old is given internet-based homework every week. And they are both absolutely repulsed by the idea of smoking. That was not the prevailing sentiment when I was young.…
开发者
Roundtables: Longevity’s Next Frontier: “Reprogramming” Your Body
Listen to the session or watch below Billions of dollars are flooding into efforts to reverse aging as scientists explore ways to return cells to a younger state. But how far off are these experimental treatments? Will they really work? Watch a conversation exploring longevity’s new focus. Speakers: Mary Beth Griggs, science editor and Jessica…
AI 资讯
Anthropic’s Claude Science bets on workflow, not a new model, to win over scientists
Anthropic's Claude Science is a workbench that gives scientists one environment to do computational research, saving them from the need to bounce between databases, pipelines, and tools.
创业投融资
Early Bird pricing ends tonight for TechCrunch Founder Summit
Save up to $190 on your pass to TechCrunch Founder Summit 2026. Early Bird pricing ends today, at 11:59 p.m. PT, after which rates increase. Register now.
AI 资讯
Heat waves mess with your brain. Scientists are trying to figure out why.
It’s been hot in London this week. Really hot. A dangerous heat wave has hit Western Europe. Yesterday, the UK recorded its highest ever June temperature at 36.1 °C (about 97 °F). But as the weather app on my phone confirmed, it felt like 39 °C. It’s frightening that we are seeing such temperatures in…